Hantaviruses

DNA virus, enveloped, Family: Bunyaviridae.
 
Prevalence
Rare.
 
Diagnosis
Serology.
 
Disease
No clinical signs in infected rodents.  
 
Strains
Hantaan, Prospect Hill, Puumala, Dobrava, Seoul, Sin Nombre.
 
Screening
Prior to entry to a facility.
 
Transmission
Direct contact or contact with urine or faeces of infected animals.
 
Duration
Persistent infection.
 
Durability
Gaseous formalin or vaporised hydrogen peroxide is effective. 
 
Significance
Zoonosis with severe disease of the kidneys and vascular system or the respiratory system.  
 
Control
Pathogen exclusion. Hysterectomy rederivation and embryo transfer. 
 
Reading
  • Infectious Diseases of Mice and Rats National Research Council 1991.
  • Pathology of Laboratory Rodents and Rabbits, 3rd Edn., Dean H Percy & Stephen W Barthold, 2007.
  • University of Missouri, Research Animal Diagnostic Laboratory website, http://www.radil.missouri.edu